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Lactic Acid Dehydrogenase (LDH) Exam Overview Lactic acid dehydrogenase (LDH) is an enzyme that helps produce energy. It is present in almost all of the tissues in the body and its levels rise in response to cell damage. LDH levels are measured from a sample of blood taken from a vein. Why It Is Done LDH levels help diagnose lung disease, lymphoma , anemia , and liver disease. They also help determine how well chemotherapy is working during treatment for lymphoma. Results Lactic acid dehydrogenase (LDH) is an enzyme that helps produce energy. Results may vary widely from lab to lab. Normal LDH levels range from 140 units per liter (U/L) to 280 U/L or 2.34 mkat/L to 4.68 mkat/L.